Category Archives: Clinical Reference

Assessing Clinical Evidence

There are always numerous opinions regarding the relevance and quality of clinical studies. As we seek to determine the validity of conclusions given by authors, it is important to develop a consistent approach to the evaluation of the evidence. Here is one such method: 1) What is the question being asked? This is important to understand before proceeding further because

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Tranexamic Acid (TXA)

Tranexamic acid is a synthetic form of lysine, an amino acid. It is classified as an “anti-fibrinolytic” which means it is a  pro-coagulant. It binds to receptors on plasmin preventing it from breaking down fibrin clots. Tranexamic acid was originally discovered in 1962 and is currently on the World Health Organization’s list of Essential Medicines.  The drug has been studied

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