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DKA and HHS

Definitions: Diabetic ketoacidosis (DKA)1,2– uncontrolled hyperglycemia, metabolic acidosis, and increased total body ketones Hyperosmolar hyperglycemic state (HHS)1,2– severe hyperglycemia, hyperosmolality, and dehydration in the absence of significant ketoacidosis Treatment: Fluid resuscitation:1,2 NS (0.9%NaCl) 15-20 ml/kg or 1-1.5 liters in first hour … THEN If corrected serum Na is low, cont. NS @ 250-500 ml/hr If corrected serum Na is high

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