Varicella & Pregnancy

Treatment in pregnancy: Chicken Pox Infection Immunized or Hx of past infection: exposure: nothing to do. simple rash: acyclovir 800mg PO 5x/day for 7 days severe infection or pneumonia, admit for IV acyclovir and supportive care. Not Immunized: exposure: consider VZIG, give first dose within 96 hours if possible, and up to 10 days from exposure. simple rash: acyclovir 800mg

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Tranexamic Acid (TXA)

Tranexamic acid is a synthetic form of lysine, an amino acid. It is classified as an “anti-fibrinolytic” which means it is a  pro-coagulant. It binds to receptors on plasmin preventing it from breaking down fibrin clots. Tranexamic acid was originally discovered in 1962 and is currently on the World Health Organization’s list of Essential Medicines.  The drug has been studied

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Criteria Pregnancy, 20 weeks gestation up to 6 weeks postpartum, AND Hypertension >140/90 x 2 (at least 4 hours apart) or >160/110 x 2 (minutes apart) in a woman who was previously normotensive AND any one of the following: Proteinuria, defined as urine dipstick >1+ or >0.3 g in a 24-hour period Platelets <100k/mcL Serum creatinine > 1.1 mg/dL Liver transaminases

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